---
title: "Neogen vs. Microneedling vs. CO2 Laser: Which Is Best?"
url: https://icryo-westminster.com/blog/neogen-vs-microneedling-vs-co2-laser
description: "Compare Neogen plasma, microneedling and CO2 laser for wrinkles, texture and scars, including how they work, downtime and who each is best for."
lang: en
---

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# Neogen vs. Microneedling vs. CO2 Laser: Which Is Best for Your Skin?

Updated October 20, 2026 · 2 min read

Image: Neogen facial treatment beside the plasma device — iCRYO Westminster, CO wellness guide (https://icryo-westminster.com/__l5e/assets-v1/f5cd2697-2053-41b5-b013-ec6d0ba31f62/icryo-westminster-co-neogen-vs-microneedling-vs-co2-laser.webp)

When it comes to skin renewal, three treatments come up again and again: **microneedling**, **CO2 laser** and **Neogen plasma**.

All three aim to renew skin and build collagen, but they get there in very different ways. Here's how to choose.

## How Each Treatment Works

## Microneedling

A device creates tiny punctures in the skin. Your body responds by producing collagen to repair them.

## CO2 laser

An ablative laser removes thin layers of skin or creates columns of injury, triggering deep renewal and collagen production.

## Neogen plasma

Nitrogen plasma delivers even heat to the skin. The treated skin stays in place as a natural dressing while fresh skin forms underneath, and collagen builds for months. Learn more in What Is Neogen? (https://icryo-westminster.com/blog/what-is-neogen-plasma)

## Side-by-Side Comparison

| | **Neogen Plasma** | **Microneedling** | **CO2 Laser** |
| --- | --- | --- | --- |
| **How it works** | Nitrogen plasma heats skin evenly | Tiny needles create micro-injuries | Laser removes or vaporizes skin |
| **Fine lines** | Yes | Mild improvement | Yes |
| **Texture and tone** | Yes | Yes | Yes |
| **Acne scars** | Yes | Yes | Yes |
| **Skin tightening** | Yes | Mild | Yes |
| **Around the eyes** | Yes | Limited | Requires caution |
| **Downtime** | Adjustable | Usually short | Often longest |
| **Sessions needed** | Fewer per result | Several | Often one |

## When Microneedling Makes Sense

- You want very little downtime
- Your concerns are mild
- You're comfortable with several sessions

## When CO2 Laser Makes Sense

- You have significant damage
- You can take extended time off for healing
- You've talked with a provider about the higher risks

## When Neogen Makes Sense

- You have multiple concerns, like lines, texture, tone and scarring
- You want to treat around the eyes
- You want strong results with control over downtime
- You'd like collagen-building that keeps improving for months

See the full list in Neogen Plasma Benefits (https://icryo-westminster.com/blog/neogen-plasma-benefits).

## What About Skin Type?

Every treatment carries some risk of pigment changes, especially in darker skin tones. Your provider will evaluate your skin type and recommend the safest approach.

## Not Sure Which Is Right for You?

At your consultation, we'll assess your skin and goals and recommend the treatment and intensity that fits. Want to know what recovery looks like? Read Neogen Downtime and Results (https://icryo-westminster.com/blog/neogen-downtime-results).

Ready to find your best skin treatment?

## Neogen Face Lift in Westminster, CO

iCRYO Westminster is at **14613 Orchard Pkwy #200, Westminster, CO 80023**, just off I-25 with free parking. We welcome clients from Broomfield, Thornton, Northglenn, Arvada, Federal Heights and north Denver.

- See our current intro offers: https://icryo-westminster.com/deals
- Book your intro visit: https://icryo-westminster.com/book-now
- Get your free personalized wellness plan: https://icryo-westminster.com/free-wellness-plan

Questions? Call (720) 222-0224.

## Neogen Face Lift FAQs

Is Neogen better than microneedling?

They work differently. Microneedling creates tiny punctures to trigger collagen. Neogen heats the skin evenly with plasma, which can address texture, tone, lines and laxity together. Neogen is often more powerful per session.

Is Neogen better than CO2 laser?

CO2 laser is very powerful but usually involves more downtime and higher risk. Neogen offers significant results with adjustable downtime, and the treated skin stays in place as a natural dressing while you heal.

Which treatment has the least downtime?

Microneedling usually has the shortest downtime. Neogen's downtime depends on intensity, and CO2 laser typically has the longest.

Can Neogen treat the eyelids?

Yes. Neogen can be used around the eyes, an area that many other resurfacing treatments avoid.

iCRYO Westminster Team

The iCRYO Westminster team helps clients across the north Denver metro look and feel their best.

## Related Articles

What Is Neogen Plasma Skin Regeneration?

Neogen uses nitrogen plasma to renew skin from within for fine lines, texture, tone and acne scarring. Learn how it works at iCRYO Westminster, CO.
https://icryo-westminster.com/blog/what-is-neogen-plasma

Neogen Plasma Benefits for Fine Lines, Texture and Tone

Neogen treats fine lines, texture, sun damage, acne scars and crepey eyelids in one treatment. See the top benefits of plasma skin regeneration.
https://icryo-westminster.com/blog/neogen-plasma-benefits

Neogen Downtime and Results: Day-by-Day Recovery

What happens after Neogen? See a day-by-day recovery timeline, aftercare tips and when you'll see results from plasma skin regeneration in Westminster, CO.
https://icryo-westminster.com/blog/neogen-downtime-results

Learn more about Neogen Face Lift in Westminster, CO

View the Neogen Face Lift service page →
https://icryo-westminster.com/services/neogen

Start your wellness journey in Westminster

Get Your Free Wellness Plan: https://icryo-westminster.com/free-wellness-plan
Book Your Intro: https://icryo-westminster.com/book-now

(720) 222-0224 (+17202220224)

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